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PMBPs induce loss of mitochondrial membrane potential.

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posted on 05.11.2015, 03:38 by Jia Liu, Jing Bai, Guoqiang Jiang, Xinli Li, Jing Wang, Dachang Wu, Lawrence Owusu, Ershao Zhang, Weiling Li

(A) The A2780 and OV2008 cells were treated with PMBPs (0, 25, 35, 50 μg/ml) for 24 h and then harvested, stained with JC-1 dye, and finally analyzed by flow cytometry. (B) PMBPs treatment resulted in a significant increase of green fluorescence positive (GFP) cells which indicated the loss of mitochondrial membrane potential. The experiments were repeated three times. **P<0.01 compared to the control group.