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PMBPs impaired the migration and invasion of ovarian cancer cells as assessed by transwell chamber assay.

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posted on 05.11.2015, 03:38 by Jia Liu, Jing Bai, Guoqiang Jiang, Xinli Li, Jing Wang, Dachang Wu, Lawrence Owusu, Ershao Zhang, Weiling Li

A2780 and OV2008 cells were treated with PMBPs (0, 5, 10, 25 μg/ml) for 24 h. (A) Representative images of cells that migrated and invaded onto the underside of transwell membrane at 100× magnification under a microscope. (B,C) Number of cells of each field was counted and averaged. Invaded cells were expressed relative to that of control group. The experiments were repeated three times. **P<0.01 and ***P<0.001 compared to the control group.