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Kinetics of viral propagation at days 1 and 3 after Cl13 infection.

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posted on 08.01.2015, 03:30 by Brian M. Sullivan, John R. Teijaro, Juan Carlos de la Torre, Michael B. A. Oldstone

C57Bl6/J mice (n = 4/group) were mock (PBS) primed or ArmΔGPC (2×106,i.v.) primed and 10 hours later infected with Cl13 (2×106,i.v.)). Organs were harvested at 24 (top panel) and 72 (bottom panel) hours post-infection and homogenates prepared in RPMI containing 10% FBS. Virus titers in clarified homogenates were determined as in Fig. 1. Statistical analysis was done using t-tests of log transformed values. NS, not significant; ND, none detected; *p<0.05; **p<0.005; **p<0.0005. Graphs are representative of three independent experiments.