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Immuno-histochemical staining, and disease-specific survival of fibulin-5 in patients with NPC.

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posted on 27.12.2013, 02:45 by Chung-Feng Hwang, Li-Yen Shiu, Li-Jen Su, Yu-Fang Yin, Wei-Sheng Wang, Shun-Chen Huang, Tai-Jan Chiu, Chao-Cheng Huang, Yen-Yi Zhen, Hsin-Ting Tsai, Fu-Min Fang, Tai-Lin Huang, Chang-Han Chen

(A) The intensity of fibulin-5 expression in various tissues by immunohistochemical staining were evaluated in (a) normal tissue and tumor tissues of NPC patients with stage I (b), II (c), III (d), IV (e), lymph node-negative (f), and lymph node-positive (g) samples. Original magnification, 200×. (B) Survival of patients with high fibulin-5 expression (solid line) was significantly abbreviated in comparison to those with low expression (dashed line), with a statistically significant difference in survival (p = 0.003) by log-rank test.

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