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Illustration of biological function modules that were affected by drug combinations and were significantly implicated in the regulation of cell apoptosis (false discovery rate <0.05).

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posted on 05.02.2014, 03:33 authored by Xiaojing Wan, Jia Meng, Yingnan Dai, Yina Zhang, Shuang Yan

A. An apoptosis regulatory module affected by the 2-drug combination of celecoxib and silibinin; B. Apoptosis regulatory modules affected by the 2-drug combination of curcumin and silibinin; C. An apoptosis regulatory module affected by the 2-drug combination of curcumin and celecoxib; D. An apoptosis regulatory module affected by the 3-drug combination of curcumin, celecoxib, and sulforaphane; E. Apoptosis regulatory modules affected by the 3-drug combination of curcumin, celecoxib, and silibinin; the yellow node represents a network target that is involved in the regulation of cell apoptosis.

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