Example of LFP data analysis procedure.

(a) Example of a vector field before a wave enters the microelectrode array. For each of the interior electrodes, an angle is assigned according to the gradient. (b) Example weighted angle distribution for the time interval (t₀ − 14 ms, t₀ + 100 ms) for a single wave during a seizure. In this example, t_initial = 14 ms and t_final = 100 ms. The peak of the distribution occurs at angle θ₀. (c) Illustration of the different computed quantities: θ₀ is the peak of the distribution; θ₁ = θ₀+180c, where c = ±1 (depending on the value of θ₀); t_initial is the time at which the phase interval (θ₀-20, θ₀+20) acquires non-zero counts; t₀ is the time at which the LFP z-scored signal at the center of the microelectrode array exceeds a threshold; and t_final is the last time at which counts appear in the angular interval around θ₁.