Effect of claudin-18 knockdown on the proliferation and invasion of GC cells.
(A) Claudin-18 siRNA treatment significantly induces cell proliferation. (B) Claudin-18 siRNA-transfected MKN74 cells show a significantly higher invasion ratio compared to control or control siRNA-transfected cells. Typical images are presented at the top. Bar = 500 µm. Each value represents the mean ± SD of 3 independent experiments. **P<0.01 vs. control or control siRNA.