Figure_4.tif (3.09 MB)
Effect of acute ethanol exposure on DNA-strand breaks in cardiomyocytes.
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posted on 2013-02-19, 20:17 authored by Shiliang Li, Sevil Korkmaz, Sivakkanan Loganathan, Alexander Weymann, Tamás Radovits, Enikő Barnucz, Kristóf Hirschberg, Peter Hegedüs, Yan Zhou, Liang Tao, Szabolcs Páli, Gábor Veres, Matthias Karck, Gábor SzabóRepresentative photomicrographs of (A) cardiomyocytes stained with cardiac troponin I (green) and nuclei with 4′, 6-diamidino-2-phenylindole (DAPI, blue), (B) nuclei with fragmented DNA visualized by TUNEL staining (red), and (C) merged image. Magnification ×400; scale bar: 20 µm. White arrows indicate TUNEL-positive cells (not all are marked) (D) Quantification of TUNEL-positive cells. We found DNA damage in the myocardium of rats treated with ethanol at 24 h. Eth indicates ethanol. *p<0.05 versus control.