Fig_7.tif (233.96 kB)
ENaC mRNA transcript expression and activity in colon from CAP2/Tmprss4 mice under sodium-deficient diet.
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posted on 2015-08-26, 04:27 authored by Anna Keppner, Ditte Andreasen, Anne-Marie Mérillat, Julie Bapst, Camille Ansermet, Qing Wang, Marc Maillard, Sumedha Malsure, Antoine Nobile, Edith Hummler(A-C) Relative mRNA transcript expression of (A) Scnn1a, (B) Scnn1b and (C)Scnn1g from CAP2/Tmprss4 wildtype (WT, n = 4), heterozygous mutant (HET, n = 5), and knockout (KO, n = 4) mice; *P< 0.05); β-actin was used as internal control. (D) Morning and afternoon amiloride-sensitive rectal potential difference (PD) measurements at 10-12am and 4-6pm of two consecutive days in Tmprss4 wildtype (WT), heterozygous mutant (HET) and knockout (KO) mice; n = 4 for each group and genotype.
