Figure_1.tif (369.75 kB)
Different inbred laboratory mouse strains exhibit variable kinetics of weight loss and survival after infection with Influenza A virus.
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posted on 2013-02-21, 06:29 authored by Barkha Srivastava, Paulina Błażejewska, Manuela Heßmann, Dunja Bruder, Robert Geffers, Susanne Mauel, Achim D. Gruber, Klaus SchughartC57BL/6J, DBA/2J, FVB/NJ, CBA/J, BALB/cByJ, A/J and SJL/JOrlCrl mice were infected intra-nasally with 2×103 FFU of PR8 virus. Weight loss and survival of infected mice was followed over a period of 14 days. Mortality also includes mice that were sacrificed because they had lost more than 25% of body weight. Mean percent of body weight change (±SEM) for each group of inbred strains is shown. For DBA/2J and C57BL/6J mice, data are from two independent experiments. Statistical analysis of pair wise comparisons for all strains and days are presented in table 1.