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Comparison of the Nrf1 expression under hypoxia and proteasomal inhibition.

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posted on 21.12.2011, 00:11 by Nikolai L. Chepelev, Joshua D. Bennitz, Ting Huang, Skye McBride, William G. Willmore

WFF2002 (A) and COS7 (B) cells were treated with normoxia (21% O2), hypoxia (1% O2), 10 µM MG-132 or hypoxia and MG-132 combination for six hours and subjected to Western blotting. The band density was normalized with respect to β-tubulin (β-tub) or ponceau S red staining (p. stain) and is presented as means ± SEM of at least three independent experiments for WFF2002 (C) and COS7 (D) cells. Asterisks (*) indicate significant difference (p<0.05) compared to control.

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