Changes in alpha4-beta7 integrin expression on dividing CD8⁺ T cells.

The level of expression of alpha4-beta7 integrin was calculated as the geometrical mean fluorescence intensity and is presented as a function of cell division for each individual mouse. In the MLN, there were increase in alpha4-beta7 integrin expression in both control and CD4+ treated mice, but the increase in GMFI was significantly greater in control mice (p = 0.0325). Data are from three experiments (n = 2 mice per group per experiment). A GMFI of >0 implies fluorescence intensity lower than the unstained control.