BMPR2 mRNA expression in visceral (Vis) and subcutaneous (SC) adipose tissue in lean, obese and type 2 diabetic subjects.

The data are means ±SEM; BMPR2 mRNA levels in (A) men (N = 80) and women (N = 81), (B) subgroups of lean (BMI <25 kg/m²; N = 44), overweight (25 kg/m² < BMI <30 kg/m²; N = 37), SC obese (N = 57) and Vis obese (N = 23) (BMI >30 kg/m²); (C) subjects with normal glucose tolerance (NGT; N = 116) and with impaired glucose tolerance (IGT; N = 15) or with type 2 diabetes (T2D; N = 30). * and *** indicate statistical significance at P<0.05 and P<0.001, respectively when compared with expression in lean subjects (Figure B) or in subjects with NGT (Figure C); # indicates statistical significance for differences between fat depots (Vis vs. SC) for appropriate subject groups; ^## and ^### indicate statistically significant at P<0.01 and P<0.001, respectively. AU, arbitrary units.