Antibody Ratios Found in Patients with NMO and in Patients with Relevant Differential Diagnoses or Healthy Controls

Each individual value represents the result from a single serum sample tested twice with the AQP4 RIPA. Black horizontal bars represent mean. The dashed horizontal line indicates the cutoff at an antibody ratio of 11. Diagnostic categories: NMO, neuromyelitis optica; LETM longitudinally extensive transverse myelitis; MS/ON+, multiple sclerosis with optic neuritis; MS/ON−, multiple sclerosis without optic neuritis; ON, optic neuritis; MYL, myelitis extending over fewer than three vertebral segments on MRI; OIND, other inflammatory neurological disorders and systemic disorders with neurological involvement (e.g., neuroborreliosis, chronic inflammatory demyelinating polyneuropathy; for exact classification see legend for Table 1); OND, other noninflammatory neurological diseases (e.g., carpal tunnel syndrome); RD, rheumatological diseases without neurological involvement (for exact classification see legend for Table 1); HC, healthy controls.