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Waking behavior observation protocol.

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posted on 2018-10-29, 17:28 authored by Lukas Mees, Jonathan Fidler, Matthias Kreuzer, Jieming Fu, Machelle T. Pardue, Paul S. García

Timeline describing observation protocol. Procedures listed on top, with behaviors listed below. K/X: ketamine/xylazine, LORR: loss of righting reflex, RORR: return of righting reflex.

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    ketamineyohimbineRORRantagonistrighting reflexYOH administrationintraperitoneal injectionsselectivityanesthesia inductionwhisker movementemergence sequenceATIpharmacokinetic effectsmotor behaviorbehavior post-anesthesiamgre-animation sequenceantagonizing GABA receptorsα 1emergence behavior

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