pone.0295069.g002.tif (1.14 MB)
Vertex-wise group differences in the rate of change of cortical thickness.
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posted on 2024-01-31, 18:30 authored by Andrzej Sokołowski, Nikhil Bhagwat, Yohan Chatelain, Mathieu Dugré, Alexandru Hanganu, Oury Monchi, Brent McPherson, Michelle Wang, Jean-Baptiste Poline, Madeleine Sharp, Tristan GlatardCold colors represent increased cortical thinning in the first group compared to the second group, warm colors represent increased cortical thinning in the second group compared to the first group. Results corrected with the cluster-wise threshold (p < .05). HC, healthy controls; PD-MCI, Parkinson’s disease with mild cognitive impairment; PD-non-MCI, Parkinson’s disease without mild cognitive impairment.
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xlink ">( 1magnetic resonance imagingleft inferior temporalhanganu et alexisting major challenge18 healthy controlsprogression markers initiativeparkinson &# 8217mild cognitive impairmentjama neurology recent survey (<pd patients correlatedpatients without mcipd neuroimaging findingspd patientsparkinson ’cognitive performancecognitive declinebrain 78 137 subcortical volumessubcortical structuresstructural changessample sizerobust enoughprecentral gyripotential sourcegroup differencesdisease progressiondespite differencesdataset usedcortical thinningcortical thickness>( 10
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