Utility of MLAST in an efficacy trial using Kras/Lkb1 GEM model.

(A) Manual scores assigned to scans from vehicle control (blue) and drug treatment (pink) groups before (baseline) and 3 weeks post-treatment regimen. (B) MLAST scores from vehicle (blue) and drug treatment (pink) groups before and post-treatment regimen. (C) Representative images from vehicle control and drug treated groups before and post-treatment. Images show profound progression of tumor in vehicle control group, but not in drug treated group. (n = 10/group; +/- SEM; ** = p-value < 0.0001).