pntd.0010151.s004.TIF (818.16 kB)
Urine IgG recognition of thioredoxin from Zimbabwean infected individuals with different infection intensities.
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posted on 2022-01-24, 18:39 authored by Gebeyaw G. Mekonnen, Bemnet A. Tedla, Mark S. Pearson, Luke Becker, Matt Field, Abena S. Amoah, Govert van Dam, Paul L. A. M. Corstjens, Takafira Mduluza, Francisca Mutapi, Alex Loukas, Javier SotilloThe antibody level was measured by indirect ELISA and indicated by OD values. Urine of non-infected individuals from non-endemic area was used as negative control. The reactivity cut-off values were determined by adding the average and 3x standard deviation of non-endemic negative individuals (indicated by broken lines).
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provides compelling evidencehost immune systemcirculating anodic antigennovel diagnostic markerslarge extracellular loopsbacterial expression systemurine igg responsesdifferentially expressed throughoutdifferent parasite proteomespotential diagnostic valueschistosoma haematobium diagnostic capabilityhaematobium extracellular vesiclesexpression withinwork presentedurogenital schistosomiasissoluble excretorysh secretory productsrobust associationrecombinant proteinspolyclonal antibodiesmrnas encodingmicroscopy ).low levelsleading causeinternal tissuesimmunologically diagnoseendemic areabladder cancerbiomarker signatureassessed usinganatomical sitesadult parasitesabundantly present>- tsp
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