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Time course of HF16 hairpin ribozyme-catalyzed cleavage of unmodified (circles), 2′-NH-modified (squares) and photo-crosslinker -modified (triangles) substrate

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posted on 31.12.2011, 05:00 by Emily J. Borda, Snorri Th. Sigurdsson

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Taken from "Investigation of Mg- and temperature-dependent folding of the hairpin ribozyme by photo-crosslinking: effects of photo-crosslinker tether length and chemistry"

Nucleic Acids Research 2005;33(3):1058-1068.

Published online 18 Feb 2005

PMCID:PMC549404.

© The Author 2005. Published by Oxford University Press. All rights reserved

Insert shows an expansion of early time points. SD values were 2, 2, 3 and 4% for 2′-NH-modified HF16 activity and 0.4, 2, 3 and 1% for -modified HF16 activity at 0.5, 1, 30 and 120 min, respectively.

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