pcbi.1011252.g003.tif (364.98 kB)
The first four days post radiotherapy (Day 0 is the day of irradiation).
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posted on 2024-02-16, 18:33 authored by Jakub Köry, Vedang Narain, Bernadette J. Stolz, Jakob Kaeppler, Bostjan Markelc, Ruth J. Muschel, Philip K. Maini, Joe M. Pitt-Francis, Helen M. ByrneTime evolution of (A) vessel count NV and (B) perfusion fraction for the 7 tumours studied in [15].
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small mean diametersnovel computational modelconsidering network compositionangiogenic sprouts showtumour angiogenesis leadsalso identify casessupport blood flowdiv >< pperfusion increases duepoor blood perfusionoptimal irradiation strategyoptimal strategytumour ’largest increasesidentify tumoursblood perfusionperfusion postperfusion enhancementvivo vascular tumoursvascular networkssynthetic tumoursspatially heterogeneoussilico results indicateregular deploymentoxygen heterogeneitylarge numbersincreased hypoxiaimaging datagood candidatescombination therapiesarchitectural features
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