pntd.0010982.g003.tif (417.62 kB)
The close relationship between the index case and family member isolates from households 25 and 44 shown with a phylogenetic tree.
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posted on 2022-12-12, 18:35 authored by Leonard Koolman, Reenesh Prakash, Yohane Diness, Chisomo Msefula, Tonney S. Nyirenda, Franziska Olgemoeller, Paul Wigley, Blanca Perez-Sepulveda, Jay C. D. Hinton, Siân V. Owen, Nicholas A. Feasey, Philip M. Ashton, Melita A. GordonWhole genome maximum likelihood tree of 19 S. Typhimurium isolates described in Table 2. The numbers at the end of each branch indicate household, as described in the first column of Table 2 (all these households are case households). Sequencing read sets were compared against the reference genome D23580 as described in Methods.
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yielded 43 nonhealthy typhoid (<oct 2016 ).household environment demonstratedeight invasive nonmatched household membershealthy household members28 ints patientssixty index caseshousehold environment suggestsnts strains foundmatched control householdsinvasive salmonella diseasehealthy peoplecontrol householdinvasive strainssts ).index casessalmonella typhimuriumnts strains25 households120 householdscontrol studycontrol investigationgeographically matchedhousehold samplingsaharan africarelated animalrectal swabsmethodological developmentmarch 2015mainly st313ints infectionsdiverse rangediverse ecologycarrier state6 %).3 sts1203 samples
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