pone.0255736.g010.tif (2.09 MB)
The binding site of the potential bioactive components and the core target protein AKT1.
figure
posted on 2021-09-28, 17:34 authored by Kedi Liu, Xingru Tao, Jing Su, Fei Li, Fei Mu, Shi Zhao, Xinming Lu, Jing Li, Sha Chen, Taiwei Dong, Jialin Duan, Peifeng Wei, Miaomiao XiA:MOL002974, B:MOL002975, C:MOL002914, D:MOL002959, E:MOL003003. The blue solid lines represented hydrogen bondings, and the gray dashed lines represented hydrophobic interactions.
History
Usage metrics
Categories
Keywords
could significantly improve0 threonine residues5 bioactive components29 bioactive componentsslightly better effectenrichment analysis showeddalbergia odoriferain protectingpossible bioactive componentscerebral infarction volumemolecular docking revealmolecular docking predicatetreating ischemic strokediv >< pdetecting neurological scorepossible effective substancesmolecular dockingneurological scoreeffective substances12 componentsprotective effectdalbergia odoriferacerebral tissuecerebral ischemiapossible mechanismsdocking resultswidely usedvivo vitro used toelucidatestill unclearsecondary developmentresearch revealsrelated targetsrat modelnew directionnetwork pharmacologylactate dehydrogenaseexperiments showeddependent mannercontained 2cerebrovascular diseasesinclinicalbinding sitesakt phosphorylation
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC