pone.0297625.g003.tif (321.81 kB)
The binding of 101 phages with OHC and NT1 sera.
figure
posted on 2024-03-05, 18:27 authored by Thi-Tuyet Trinh Tran, Thi-Hong Nhung Nguyen, Yves Dauvilliers, Roland Liblau, Xuan-Hung NguyenAfter five rounds of positive and negative biopanning, 101 randomly selected phage clones were evaluated for binding to IgG from pooled OHC and NT1 serum via phage ELISA (n = 3). The binding of phage with OHC pooled serum-derived and NT1 pooled serum-derived IgG are analyzed by multiple unpaired t-tests with p<0.05.
History
Usage metrics
Keywords
neurons producing orexinnarcolepsy type 1mediated immunity ratherdifferential binding capacityalso named hypocretinserum immunoglobin gnt1 patient cohortunbiased random peptidespecific antigens targetedohc control groupmer peptides derivednt1 serum iggtargeted methodologiesspecific autoantibodiesvarious peptidesstatistically significantselective lossselected usingrtn4 proteinsprevious studiesorexinergic neuronohcs ).lateral hypothalamushypersomnolence complaintshigh reactivityautoimmune responseautoimmune disease
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC