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The Potential of death induction (Pdeath) of cancer cells increases over time upon cytotoxic death, but not upon natural death.

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posted on 2021-03-30, 17:41 authored by Irina Veith, Arianna Mencattini, Valentin Picant, Marco Serra, Marine Leclerc, Maria Colomba Comes, Fathia Mami-Chouaib, Jacques Camonis, Stéphanie Descroix, Hamasseh Shirvani, Fatima Mechta-Grigoriou, Gérard Zalcman, Maria Carla Parrini, Eugenio Martinelli

A. Representative Pdeath analysis on one video of breast cancer MDA-MB-231 cells cultured within ToC without (left, natural death) or with 1 μM doxorubicin (right, cytotoxic death). B. Representative Pdeath analysis on one video of NSCLC IGR-Pub cells cultured within ToC alone (left, natural death) or together with autologous CTL (P62 clone) (right, cytotoxic death). C. Representative Pdeath analysis on one video of breast cancer MDA-MB-231 cells co-cultured with CAFs within ToC, without (left) or with 1 μM doxorubicin (right). More video analyses on additional view fields are shown in S2 Fig.

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