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TcdB1 and TcdB3 have the same potential to bind FZD proteins.

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posted on 2021-01-28, 18:27 authored by Zhenrui Pan, Yuanyuan Zhang, Jianhua Luo, Danyang Li, Yao Zhou, Liuqing He, Qi Yang, Min Dong, Liang Tao

(A) Primary sequence alignment of the FZD-binding region (1421–1620) between TcdB1 and TcdB3. The only different residue (1575) is highlighted by red. (B) Illustrated representation of TcdB-FZD2 complex, with TcdB in green and FZD2 in cyan. The position of S1575 in the structure is marked by an arrow.

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