pone.0245917.s001.tif (67.9 kB)
TCR-Vβ profile of huCD3ε-bearing T cells.
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posted on 2021-02-17, 18:34 authored by Joel Crespo, Yi Ting Koh, Ningjie Hu, Paul A. Moore, Ezio Bonvini, Andrew L. Glasebrook, Andrea P. Martin, Robert J. Benschop(A-B) TCR-Vβ profile of 2-month old WT, huCD3eHET and huCD3eHOM CD4+ and CD8+ T cells. n = 8, *p<0.05.
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CD 3 antibodiesdrug candidatesT cell-dependent antigenstype miceCD 3.knock-in modelCD 3 therapy Pre-clinical murine modelsT cellantibody titersgraft-vs-host disease modelCD 3thymocyte developmentCD 3 therapy worksresults showeffector T cell responseshumanized CD 3 murine modelhuCD 3ε HET micehuCD 3ε HET T cellshumanized-CD 3ε-exon
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