pone.0294976.g001.tif (1.57 MB)
T1w, T2w, DWI and ADC maps of 4 representative patients with germ cell tumors.
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posted on 2023-11-30, 19:03 authored by Carlos Eduardo Bezerra Cavalcante, Fernanda Magalhães Pereira Souza, Gisele Eiras Martins, Marcelo Milone Silva, Carla Renata Pacheco Donato Macedo, Henrique Lederman, Luiz Fernando LopesHypersignal areas are observed in the diffusion sequence (DWI) showing correlation with areas of signal loss on the ADC map (ADC) denoting restricted movement of water molecules and high cellularity. The red box corresponds to the zoomed area represented in the ROI column. The red circle represents the ROI, and the white box represents the measured mADC value. ROI: region of interest.
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nonenhancing lesion voxelsmonitor therapeutic responsemean ± sdlargest hypersignal areademonstrated reasonable evidence00 ± 37200 ± 16800 x 1050 ± 161primary gcts treatedpediatric gcts needspediatric extracranial gctssup >&# 8722highest mean adcgreatest restricted diffusionapparent diffusion coefficient3 distinguish pure teratomasdifferentiated pure teratomasweighted without contrastroc analysis determinedmonitor treatment responselowest adc valuecutoff madc valueused two valuesmalignant cgt histologiesmadc assessment couldpure teratomasmalignant gctstwo radiologists00 mm50 mmyolk sacxlink ">weighted imagingvisual inspectiontumor densitysmall roisignificant increaseroi determinationroi ).mixed teratomaindirect markerhistological characteristicsheterogeneous groupfindings suggestclinical practicechallenging scenarioavoiding necroticadipose tissue76 x1001 ).
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