Supplementary Figure 1.tiff (4.36 MB)
Supplemantal Figure 1. LC-MS/MS determination of DOC, corticosterone and aldosterone over time in three ASD patients after discontinuation of fludrocortisone treatment.
Version 4 2021-07-29, 00:23
Version 3 2021-07-28, 23:37
Version 2 2021-07-28, 23:18
Version 1 2021-07-28, 23:12
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posted on 2021-07-29, 00:23 authored by Busra Gurpinar TosunBusra Gurpinar Tosun, Yasemin Kendir Demirkol, Tuba Seven Menevse, Sare Betul Kaygusuz, Mehmet Nuri Ozbek, Selda Ayça Altıncık, Jamala Mamadova, Atilla Cayir, Esra Doger, Elvan Bayramoglu, Özlem Nalbantoğlu, Gul Yesiltepe Yesiltepe Mutlu, AghaRza Aghayev, Serap Turan, Abdullah Bereket, Tulay GuranSupplemantal Figure 1. LC-MS/MS determination of DOC, corticosterone and aldosterone over time in three ASD patients after discontinuation of fludrocortisone treatment. Compared to control individuals (open circles), steroid measurements of F2P1 (A; upper panel, black squares), F3P1 (B; middle panel, black circles), and F4P2 (C; lower panel, black triangles) are presented. P values of compared measurements are shown in the upper left corner of each graph. Corticosterone and DOC were higher and aldosterone concentrations were low/normal in patients after their treatment could be discontinued which suggests ongoing insufficiency of aldosterone synthase.
