pone.0279821.s002.tif (83.59 kB)
Summary of mutation concordance and mRNA expression correlation across a panel of PDXO/PDX matched models.
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posted on 2023-01-05, 18:41 authored by Xiaoxi Xu, Rajendra Kumari, Jun Zhou, Jing Chen, Binchen Mao, Jingjing Wang, Meiling Zheng, Xiaolong Tu, Xiaoyu An, Xiaobo Chen, Likun Zhang, Xiaoli Tian, Haojie Wang, Xin Dong, Zhengzheng Bao, Sheng Guo, Xuesong Ouyang, Limei Shang, Fei Wang, Xuefei Yan, Rui Zhang, Robert G. J. Vries, Hans Clevers, Qi-Xiang Li(TIF)
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cancer stem cellspdx )/ organoidexisting pdx librarypdo ), drivenderived tumor xenograftimmune cell codiv >< pconfirmed high degree550 matched pairsmatched pairscarcinoma pdxcsc ),derived xenograftsvivo used extensivelytranslational oncologythroughput screeningsurrogate subjectspredictive modelspatients amenablelead compoundsinterchangeability ”including populationhts ).engineering enables
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