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pcbi.1011415.s001.tif (2.32 MB)

Structural alignment between FSHR-AF2 (cyan structure) and the FSHR-TM (orange structure); for reference, Cα of cysteine residues are depicted as spheres in yellow and in blue for the FSHR-TM and FSHR-AF2, respectively. The open intracellular conformation suggests that the models corresponds to the activated conformation.

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