pntd.0011803.s007.tif (698.23 kB)
Stratification of single blood cells in Stage 1 and stage 2 r-HAT cases versus controls on PC1 and PC2.
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posted on 2023-12-06, 18:35 authored by Peter Nambala, Julius Mulindwa, Harry Noyes, Vincent Pius Alibu, Barbara Nerima, Joyce Namulondo, Oscar Nyangiri, Enock Matovu, Annette MacLeod, Janelisa MusayaStratification of single blood cells in Stage 1 and stage 2 r-HAT cases versus controls on PC1 and PC2.
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significant differentially expressedfuture research whetherhuman transcriptome profilesgene expression profiles4 – 2lipid metabolism genes7 controls excluded28 healthy controlsr studio usingidentified biological pathwayshat case samplesstage 2 rgene enrichment analysisearly stage 1malawi stage 2stage 1transcriptomic profilescontrol samplesdownstream analysisdifferential analysis4519 genes1824 genes23 rrhodesiense p adjustedneutrophil activationmalawi varieslate stagesinnatedb algorithmsidentified transcriptsfunctional annotationdeseq2 packagedata addcurrent understandingclinical presentationcausative agentb age range
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