pone.0279912.g007.tif (988.99 kB)
StarD7 deficiency impairs cell migration through a reduction in p-ERK1/2, Cx43, integrin α5/β1, p-FAK protein levels.
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posted on 2022-12-30, 18:57 authored by Mariano Cruz Del Puerto, María Laura Rojas, Ana Cristina Racca, Lucille Tihomirova Kourdova, Andrea Lis Miranda, Graciela Panzetta-Dutari, Susana Genti-Raimondi, Jésica Belén Flores-MartínIt causes a disruption of the Golgi apparatus and a reduced competence to reorient the microtubule-organizing center (MTOC) during cell migration.
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integrin &# 946tumoral migratory htrmitochondrial targeting sequencestard7 knockdown interferesrestored cell migrationcx43 dependent mechanismcell migrationunknown mechanismmitochondrial homeostasismigratory capacitysvneo cellssilenced cellssignaling eventsreduced competenceorganizing centermainly releasedlipid trafficii isoformectopic expressioncx43 level
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