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Slow-wave propagation and entrainment in the GMN.

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posted on 2021-12-06, 18:28 authored by Md Ashfaq Ahmed, Sharmila Venugopal, Ranu Jung

(A) Spatiotemporal plot of the SM cell membrane potential along the length of the stomach (vertical axis) and time (horizontal axis) of all 42 SM cells of the network. The direction of slow-wave propagation occurs from the rostral end of the network (representing the mid-corpus) to the caudal end (representing the terminal antrum). (B) The membrane potential of 7 equidistant SM cells in the 42-cell network. (C) Total Lag for the first 7 cycles of simulation and the last 7 cycles of simulation. (D) Relative Lag (RL) between the 1st SM cell and ith SM cell in the network for the last 20 cycles, where i = 2, 3, 4,…, 42. (E) Spatiotemporal map of periods of all 42 SM cells in the network for the last 20 cycles. The inset plots for the Relative Lag (Fig 3D) and SM Cell Period (Fig 3E) were generated from the in vitro recordings of SM activity at different locations along the length of the cat stomach [45], where location 1 is the rostral-most recording.

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