pntd.0011803.s003.tif (206.76 kB)
Significant differentially expressed genes.
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posted on 2023-12-06, 18:35 authored by Peter Nambala, Julius Mulindwa, Harry Noyes, Vincent Pius Alibu, Barbara Nerima, Joyce Namulondo, Oscar Nyangiri, Enock Matovu, Annette MacLeod, Janelisa MusayaGene types that were significant differentially expressed in Stage 1 (A) and Stage 2 (B) r-HAT. Protein coding genes were the most differential expressed followed by lcnRNA and pseudogenes in both stage 1 and 2 r-HAT.
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significant differentially expressedfuture research whetherhuman transcriptome profilesgene expression profiles4 – 2lipid metabolism genes7 controls excluded28 healthy controlsr studio usingidentified biological pathwayshat case samplesstage 2 rgene enrichment analysisearly stage 1malawi stage 2stage 1transcriptomic profilescontrol samplesdownstream analysisdifferential analysis4519 genes1824 genes23 rrhodesiense p adjustedneutrophil activationmalawi varieslate stagesinnatedb algorithmsidentified transcriptsfunctional annotationdeseq2 packagedata addcurrent understandingclinical presentationcausative agentb age range
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