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Significant differences in the mean percentages of PD1+CD8+ (p = 0.03) and CD39+CD8+ peripheral T lymphocytes (p = 0.04) according to pathologic type (ILC, and IDC respectively), in 30 patients with TNBC (Independent t-test).

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posted on 2022-01-20, 18:28 authored by Asmaa M. Zahran, Amal Rayan, Zeinab Albadry M. Zahran, Wael M. Y. Mohamed, Dalia O. Mohamed, Mona H. Abdel-Rahim, Omnia El-Badawy

Significant differences in the mean percentages of PD1+CD8+ (p = 0.03) and CD39+CD8+ peripheral T lymphocytes (p = 0.04) according to pathologic type (ILC, and IDC respectively), in 30 patients with TNBC (Independent t-test).

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    sup >+promising treatment strategygrowing evidence highlightedcombinational immunotherapy blocking20 healthy controlsnormal breast tissuepd1 inhibitory pathwaysnegative breast cancerlymphocytes expressing pd1infiltrating lymphocytes comparedcancer tissue pd1peripheral blood samplesperipheral blood lymphocytescancer tissue cd39peripheral bloodpathways mightamong peripheraltumor tissuexlink ">tnbc ).synergistically utilizedstudy aimsignificantly increasedsignificant increaseprimary rolepositive correlationsmarked reductioninversely relatedimmune systemdisease progressiondisease course

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