ppat.1009871.g004.tif (927.23 kB)
Sharp drop in EFV levels between plasma and CSF.
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posted on 2021-09-23, 17:49 authored by Gila Lustig, Sandile Cele, Farina Karim, Anne Derache, Abigail Ngoepe, Khadija Khan, Bernadett I. Gosnell, Mahomed-Yunus S. Moosa, Ntombi Ntshuba, Suzaan Marais, Prakash M. Jeena, Katya Govender, John Adamson, Henrik Kløverpris, Ravindra K. Gupta, Rohen Harrichandparsad, Vinod B. Patel, Alex SigalMedians and IQR of EFV, FTC, and TFV concentrations in the plasma versus CSF in participants who were viremic on ART (plasma n = 32, CSF n = 31), suppressed (plasma and CSF n = 48), or showed CSF escape (plasma n = 19, CSF n = 18). Horizontal dotted line indicates limit of detection (3 ng/mL). p-values are: *< 0.05; **< 0.01; ****< 0.0001 using the Mann-Whitney U test.
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