Shared mutations at specific nucleotides across the MNoV genome were observed when passaging CR6 in vivo.

Positions throughout the MNoV CR6 genome at which a mutation was observed in more than one mouse are shown. Nucleotides are labeled by position within the genome and the protein(s) within which the mutation is found. Samples are sorted by mouse genotype and round, followed by dpi. Total sequencing reads, percentage of reads identified as MNoV, and average coverage across the MNoV genome are shown for each sample. For each mutation, individual samples are labeled in grey (indicating insufficient coverage at that position to call a mutation at that nucleotide position), yellow (sufficient coverage, and the consensus sequence of that base agrees with the reference), or red (sufficient coverage, with the consensus base differing from the reference, and with the percentage of reads differing from the reference shown in each square).

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