Sequence differences between alleles detected among TPE-containing samples from Namatanai, Papua New Guinea.

The S_E22 genotype is highly related to the sequence of TPE Samoa D, a strain isolated initially in Polynesia in 1953 [17] and sequenced later [15]. The T_E allele was divergent from TPE Samoa D and TP0858 allele 3. The TP0858 allele 3 appears to result from the intragenomic reshuffling of the TP0856 locus, a mechanism suggested earlier [18]. The predominant J_E11 genotype resembles the TPE Samoa D sequence except for allele TP0858, which was described as recombinant in the Indonesian TPE strain Kampung Dalan K363 [18]. The numbers above nucleotide positions indicate gene coordinates in the TPE Samoa D.