pntd.0010151.s002.TIF (4.22 MB)
Sequence alignment of the large extracellular loop (LEL) from six Schistosoma haematobium tetraspanins and their respective S. mansoni homolog.
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posted on 2022-01-24, 18:39 authored by Gebeyaw G. Mekonnen, Bemnet A. Tedla, Mark S. Pearson, Luke Becker, Matt Field, Abena S. Amoah, Govert van Dam, Paul L. A. M. Corstjens, Takafira Mduluza, Francisca Mutapi, Alex Loukas, Javier SotilloA multiple sequence alignment was carried out using MUSCLE with defaults and visualised using JalView.
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provides compelling evidencehost immune systemcirculating anodic antigennovel diagnostic markerslarge extracellular loopsbacterial expression systemurine igg responsesdifferentially expressed throughoutdifferent parasite proteomespotential diagnostic valueschistosoma haematobium diagnostic capabilityhaematobium extracellular vesiclesexpression withinwork presentedurogenital schistosomiasissoluble excretorysh secretory productsrobust associationrecombinant proteinspolyclonal antibodiesmrnas encodingmicroscopy ).low levelsleading causeinternal tissuesimmunologically diagnoseendemic areabladder cancerbiomarker signatureassessed usinganatomical sitesadult parasitesabundantly present>- tsp
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