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Scheme illustrating the TPSA method.

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posted on 2024-03-14, 17:47 authored by Huifang Qiu, Yuanhao Li, Min Yuan, Huali Chen, Ajai A. Dandekar, Weijun Dai

The overall procedure of the TPSA strategy developed in our study. The differentially expressed genes in each transcriptome were first determined. The common differential gene sets was then used to estimate the expression shift of down-regulated or up-regulated genes in each transcriptome by Kolmogorov-Smirnov test (KS test). Transcriptome similarity was assessed according to a ranking of the negative log10 transformed P values.

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