pone.0260155.g001.tif (1.53 MB)
Schematics of iNSA or B/E6E7equ.
figure
posted on 2021-11-19, 18:32 authored by Christoph Jindra, Edmund K. Hainisch, Andrea Rümmele, Markus Wolschek, Thomas Muster, Sabine BrandtThe Flu A or B NS1 gene was truncated to the first 106 C-terminal codons (iNS1) and shuffled BPV1 E6 and E7 sequences were inserted into the NS1 ORF.
History
Usage metrics
Categories
Keywords
unsuccessful therapeutic attemptstumour burden eventruncated ns1 genetransient side effectsystemic antitumour responseplaque assay revealedmay 2021 ).former tumour sitesassuring interferon inductionaffected individuals duesarcoids seriously compromiseb virus vectorsequ div >< pcomplete tumour regressionvirus sheddingmultiple sarcoidswell toleratedvaccination schemessynchronous regressionstill ongoingsignificantly reducingsevere formscrapings collectedsarcoid immunotherapyrepeated screeningproved safemild feverintradermal administrationinduced singlee7 antigensdeveloped influenza
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC