pone.0256846.s001.tif (1.8 MB)
Schematic representation of the study design and workflow.
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posted on 2021-09-10, 17:37 authored by Lara M. Hochfeld, Marta Bertolini, David Broadley, Natalia V. Botchkareva, Regina C. Betz, Susanne Schoch, Markus M. Nöthen, Stefanie Heilmann-HeimbachSchematic representation of the study background, the key scientifc questions, the experimental workflow, and the key findings and conclusion of the present study.
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luciferase reporter assayshaploreg database researchhair shaft formationexact molecular mechanismsdiv >< passociated variants exertunderlying pathophysiological mechanismregulatory annotations revealedmpb risk locusmpb risk allelempb lead varianttranscription factor ebf12q35 risk locusproves functional interaction>/ ebf1 interactionmale pattern baldnesspattern baldnessfunctional mechanismfunctional interactionregulatory effectregulatory architecturempb pathophysiologympb developmentpotential interactionebf1 activatesebf1 /<whose genevitro sheds lightpreviously reportedpredominant relevancefrequently observedfirst followexperiments confirmeventually resultsbinding siteassociation signal2q35 maps
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