pbio.3002425.s008.tif (372.54 kB)
Schematic representation of genetically modified Ift140 genes used in study.
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posted on 2023-12-11, 18:36 authored by Richard J. B. Francis, Jovenal T. San Agustin, Heather L. Szabo Rogers, Cheng Cui, Julie A. Jonassen, Thibaut Eguether, John A. Follit, Cecilia W. Lo, Gregory J. PazourNumbered black boxes indicate exon protein-coding regions; arrows: LoxP sites; ATG: start codon, Frt: flippase recombination target recognition site; LacZ: beta-galactosidase gene; Neo: neomycin-resistance gene.
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trunk neural cresttargeting neural cresttargeting epicardial lineageprovide novel insightsprotein regulating ciliogenesiscardiac outflow septationbody wall closurestructural birth defectsbody wall defectssbds including macrostomiadiv >< pcell autonomous rolecell autonomous multicongenital heart defectsmice craniofacial defectssbds arisingift140 er cre heart developmentwide spectrumtracheoesophageal fistulatemporospatial requirementtamoxifen induciblerostral sclerotomerenal anomaliesmediated craniofaciallate requirementintraflagellar transport
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