pone.0296775.g004.tif (3.97 MB)

Schematic diagram representing the mechanism of β-cell destruction by STZ and glucotoxicity, and the proposed mechanism of regeneration of β-cell function by CoQ10.

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posted on 2024-01-16, 18:23 authored by Yousif Jameel Jbrael, Badraldin Kareem Hamad

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conduct biochemical analyses aforementioned markers associated precipitating diabetic complications potential modulatory effect cardiac myopathy biomarkers normal control group higher serum levels coq10 per kilogram xlink "> twenty single intraperitoneal injection four male rats hematological markers correlated treated diabetic group cardiomyopathy markers improved coq10 significantly decreased fasting blood glucose basal diet supplemented xlink ">hematological markers cardiomyopathy markers fasting rats diabetic rats diabetic cardiomyopathy cardiac enzymes blood glucose beneficial effect hematological parameters serum samples serum sample coq10 may w .)three weeks three groups three days significant increases remain uninduced randomly assigned ph 4 pancreatic beta kg b hyperglycemic status hyperglycemic rats coenzyme q10 citrate buffer b ),ameliorating impact 8 ).5 g 5 ).45 mg 21 days 05 ).

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Schematic diagram representing the mechanism of β-cell destruction by STZ and glucotoxicity, and the proposed mechanism of regeneration of β-cell function by CoQ10.

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