pone.0297861.s004.tif (512.51 kB)
Scatter plots of the effects of single nucleotide polymorphisms on renal malignancies and rheumatoid arthritis; after removing outliers and tightening the P-value threshold of MR-PRESSO, SNPS associated with renal malignancies and rheumatoid arthritis funnel plot, leave-one-out and risk forest plot were obtained.
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posted on 2024-02-29, 18:46 authored by Puyu Liu, Jihang Luo, Lanlan Zhao, Qingqing Fu, Yao Chen, Chengfang Li, Jieyu Xu, Xiaorong YangScatter plots of the effects of single nucleotide polymorphisms on renal malignancies and rheumatoid arthritis; after removing outliers and tightening the P-value threshold of MR-PRESSO, SNPS associated with renal malignancies and rheumatoid arthritis funnel plot, leave-one-out and risk forest plot were obtained.
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systemic autoimmune diseaseseveral autoimmune diseasesquality control stepsprovide new insightssubacute iridocylitis (<single snp analysisconsistent without heterogeneity>), juvenile rheumatismanalyze genetic causalityinverse variance weightingwide association studyivw ), mrgenetic causalitywide genomevariance weightedcoxarthrosis (<study suggestsstudy exploresgwas ),evaluate causality897 ),xlink ">weighted modelweighted mediantemporal naturetake seriouslysimple modelsensitivity analysisscale genomerenal malignancyrenal malignanciespotential riskpotential impactpooled datapleiotropic testingodds ratiomultiple malignanciesinstrumental variablesincreased riskevaluate pleiotropydifficulty indeterminingconfidence intervalcausal relationship869 483 1 077 073 051 014 009 008 006 002
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