Scatter plot depicting each patient’s net predicted risk for stroke or systemic embolism and major bleeding.

Panel A shows the plot comparing treatment with dabigatran 110mg versus warfarin, and Panel B compares dabigatran 150mg and warfarin. Each dot represents a patient, with the net predicted risk (warfarin minus dabigatran) of stroke or systemic embolism on the y-axis, and the net predicted risk (warfarin minus dabigatran) of major bleeding on the x-axis. The further left on the x-axis, the lower the patient’s risk of major bleeding with dabigatran, and the further down on the y-axis, the lower the patient’s risk of stroke or systemic embolism.