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pone.0248747.g001.tif (2.42 MB)

SRM ion chromatograms of (A) blank hair, (B) analytes at the lower limit of quantification (50 pg/mg per AMP enantiomer), and (C) an authentic hair sample from a patient treated with Elvanse®.

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posted on 2021-03-30, 17:25 authored by Marianne Haedener, Wolfgang Weinmann, Dominique Eich, Michael Liebrenz, Thomas Wuethrich, Anna Buadze

Blue: AMP SRM1 (m/z 136.1 → 91.0); Red: AMP SRM2 (m/z 136.1 → 119.0); Green: AMP-d5 SRM1 (m/z 141.0 → 93.0). Peaks are annotated with retention times: Pane A: 10.04 min: L-AMP-d5; 11.00 min: D-AMP-d5. Pane B: 10.23 min: L-AMP; 11.14 min: D-AMP. Pane C: 11.21 min: D-AMP.

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