pntd.0011803.s005.tif (274.41 kB)
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posted on 2023-12-06, 18:35 authored by Peter Nambala, Julius Mulindwa, Harry Noyes, Vincent Pius Alibu, Barbara Nerima, Joyce Namulondo, Oscar Nyangiri, Enock Matovu, Annette MacLeod, Janelisa MusayaBiological pathways enriched in genes DE in Stage 1 blood only (A) and in Stage 2 blood only (B). Images generated by ExpressAnalyst.
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significant differentially expressedfuture research whetherhuman transcriptome profilesgene expression profiles4 – 2lipid metabolism genes7 controls excluded28 healthy controlsr studio usingidentified biological pathwayshat case samplesstage 2 rgene enrichment analysisearly stage 1malawi stage 2stage 1transcriptomic profilescontrol samplesdownstream analysisdifferential analysis4519 genes1824 genes23 rrhodesiense p adjustedneutrophil activationmalawi varieslate stagesinnatedb algorithmsidentified transcriptsfunctional annotationdeseq2 packagedata addcurrent understandingclinical presentationcausative agentb age range
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