pcbi.1011415.s004.tif (678.39 kB)
S4 Fig -
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posted on 2024-01-11, 18:40 authored by Eduardo Jardón-Valadez, Alfredo Ulloa-AguirreRoot mean squared displacement (RMSD) calculations for the Cα atoms of the transmembrane domains in FSHR (top panel) and LHCGR (bottom panel). Results for R1-R3 replicates were included.
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performed molecular dynamicslike g proteinhand coupling transversallyflexible loop knowndescribe diverse processes 945 ;-propose reaction coordinatestracking conformational transitionsfollicle stimulating hormoneidentify intermediaries suitedfshr complex suggestselectron microscopy structureprominent extracellular domaingonadotropin hormone receptorsinitial coordinatesextracellular loopschorionic gonadotropinconformational landscapeconformational changesunsaturated lipidsrich repeatspolyunsaturated phospholipidsp23945 );inactive transitionhinge regionfshr structuredefined maycoupled receptorscorrelated motionscellular transducersatom approximationallosteric regulationactivation mechanism
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