ppat.1009314.s004.tif (380.94 kB)
Male C3H/HeN mice were co-infected with antibiotic-tagged UTI89 (closed circles) and each UTI89 CUP pilus mutant (open triangles).
figure
posted on 2021-01-29, 18:42 authored by Lisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, David A. HunstadBladders (A) and kidneys (B) were harvested 2 wpi and homogenates plated on selective media. Other than ΔfimH, none of the CUP pilus mutants displayed defects in bladder or kidney colonization. Horizontal bars indicate geometric mean, and dotted line indicates limit of detection. n = 3–9 mice per condition over 5 independent experiments.
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